The initiative aims to benefit 50 million women in developing countries by 2025.
Ms Trump toured a female-run textile facility in the capital, Addis Ababa.
When his administration’s long-delayed policy on Africa was finally unveiled at the close of 2018, many observers of the continent were quick to point out that it did not include the favoured American staples: promotion of democracy, free and fair elections, political and civil rights.
The Women’s Global Development and Prosperity (W-GDP), which was launched in February, coincides with President Trump’s proposed cuts to foreign aid, and a ban on US aid to health groups that promote or provide abortions.
The W-GDP initiative aims to train women worldwide to help them get well-paying jobs.
Ms Trump visited Muya Ethiopia, a clothes manufacturing company.
The 16-year-old company, which exports clothes to the local and international markets, was founded by Sara Abera, who gave Ms Trump a tour.